Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging - 1 associated olfactory circuit degeneration in Drosophila 2
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چکیده
Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging1 associated olfactory circuit degeneration in Drosophila 2 Ashiq Hussain*, Atefeh Pooryasin*, Mo Zhang*, Laura F. Loschek, Marco La Fortezza, Anja 3 B. Friedrich, Catherine-Marie Blais, Habibe K. Üçpunar, Vicente A. Yépez, Martin Lehmann, 4 Nicolas Gompel, Julien Gagneur, Stephan J. Sigrist and Ilona C. Grunwald Kadow# 5
منابع مشابه
Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila
Loss of the sense of smell is among the first signs of natural aging and neurodegenerative diseases such as Alzheimer's and Parkinson's. Cellular and molecular mechanisms promoting this smell loss are not understood. Here, we show that Drosophila melanogaster also loses olfaction before vision with age. Within the olfactory circuit, cholinergic projection neurons show a reduced odor response ac...
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OF DISSERTATION Radhika Anand Vaishnav The Graduate School University of Kentucky 2007 MOLECULAR MECHANISMS OF OLFACTORY NEURODEGENERATION _________________________________ ABSTRACT OF DISSERTATION _________________________________OF DISSERTATION _________________________________ A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Co...
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